Molecular Endocrinology Group-03-04

Research Focus one, examine the molecular mechanism of action of phytoestrogen and their effects on cancer . The major goal of this research focus is to isolate genes (biomarkers) that may be used to study the biological function of dietary estrogens.

Research focus two involved endocrine disrupters modulating the expression of developmentally regulated genes in the male reproductive system . The major goal of this focus is to characterize the effects of environmental estrogenic compounds on male reproduction.

Research focus three involved the effect of phytoestrogen action on prostate function . The major goal of this research is to isolate genes from prostate cell that may be used as chemopreventive target for prostate cancer or to study the biological function of dietary estrogens of the prevention of prostate.

Research focus four, involves developing new and novel molecular biology approaches to phytoremediation of heavy metals . We are developing a gene expression array for screening plant for used in phytoremediation. We are screening for gene that increase a plant's ability to remediate high concentration of metals. We are applying analytical instrumentation such as MALDI-TOF-MS in identifying proteins that mediate metal transport

Molecular Endocrinology Group-98-02