Publications/Abstracts

• Criss, W.E., Muganda, P. , Sahai, A. and Morris, H.P. (1978). Cyclic Nucleotide Metabolism in Solid Tumor Tissues. In Morris Hepatomas – Mechanisms of Regulation – Advances in Experimental Medicine and Biology 92: 489-516. Morris, H.P. and Criss, W.E. (Eds). Plenum Press, N.Y.
• Muganda, P.M. (1978). New GTP Hydrolyzing Activity from the plant Momordica Charantia – Identification, Isolation and Characterization. Master's Thesis.
• Muganda-Ojiaku, P.M. (1983). Extraction of Nuclear Ribonucleoprotein Particles in Low Salt: Characterization, Magnesium Precipitation and Enzymes Associated with the Particles. Ph.D. Thesis.
• Muganda-Ojiaku, P.M. and Edenberg, H.J. (1986). Extraction and Quantitive Precipitation of Nuclear Ribonucleoprotein Particles. Preparative Biochemistry 16(1):1-20.
• Muganda-Ojiaku, P.M. and Huang, E.S. (1987). Alteration of Protein Phosphorylation Patterns in Human Cytomegalovirus-Induced Morphological Transformation. Cancer Biochemistry and Biophysics 9(2): 179-189.
• Muganda, P.M., Mendoza, O., Hernandez, J., and Qian, Q. (1994). Human Cytomegalovirus Elevates Levels of the Cellular Protein p53 in Infected Fibroblasts. J. Virology 68 (12): 8028- 8034.
• Muganda, P.M. , Fischer, A., and Bernal, R. (1995) Identification of A Casein Kinase Activity Found Elevated In Human Cytomegalovirus Transformed Cells. Biochem. Biophys. Res. Comm. 207(2): 740-746.
• Muganda, P.M. , Carrasco, R., and Qian, Q. (1998). The Human Cytomegalovirus IE286 Kilodalton Protein Elevates p53 Levels and Transactivates the p53 Promoter in Human Fibroblasts. Cellular and Molecular Biology, 44(2), 321-331.
• Yadavilli, Sridevi and Muganda, P.M. (2004). Diepoxybutane Induces Caspase and p53 Mediated Apoptosis in Human Lymphocytes. Toxicology and Applied Pharmacology 195 (2): 154-165.
• Starks, M. and Muganda, P. (2004). Genetic Engineering of Site Specific Mutations Targeting the NF-kB Binding Site Within the Human p53 Promoter. Submitted to Southern University Journal of Undergraduate Research.
• Yadavilli, S., Albrecht, T . and Muganda, P. (2004). Mechanism of p53 Elevation in Butadiene Diepoxide Exposed Fibroblasts. Manuscript in preparation.
• Yadavilli, S. and Muganda, P. (2004). Mechanisms of diepoxybutane-induced apoptosis of human lymphoblasts. Manuscript in preparation.
• Hurst, A., Yadavilli, S. and Muganda, P. (2004). Role of ERK Pathway in Diepoxybutane-Induced Apoptosis of Human Lymphoblasts. Manuscript in preparation.

Research Projects/Grants

• Recipient of National Research Service Award fellowship through institutional grant #5 T32 CA09156 awarded by National Cancer Institute, Bethesda , MD , USA . September 1984 – June 1985.
• Recipient of Minority Investigator Supplement Grant #3 R01 CA21773 07S1, Cytomegalovirus and Human Malignancy, from the National Cancer Institute. July 1985 – June 1987.
• Recipient of NIH, RR8012-19, MBRS Program at The University of Texas at El Paso subproject award from the National Institutes of Health, Bethesda , MD. , USA .
• Project title: “Protein Kinases in Cytomegalovirus Induced Neoplasia”. Subproject period: June 1, 1989 to May 31, 1991 . Total direct cost for subproject: $119,000.
• Recipient of grant#083-50-794-03, funded by The University Research Institute, The University of Texas at El Paso . Project title: “Regulation of Proto-oncogene
• Expression in Cell lines Transformed by Human Cytomegalovirus. Project Period: Dec.1, 1988-Nov. 30, 1989. Total direct cost: $6,500.
• Recipient of grant #083-50-794-15, funded by The University Research Institute, The University of Texas at El Paso . Project title: “The Role of Protein Phosphorylation on Tyrosine Residues in HCMV Induced Morphological Transformation”. Project Period: Dec. 1, 1989-Nov. 30, 1990. Total direct cost: $5,500.
• Recipient of NIH, RR8012-20, MBRS Program at The University of Texas at El Paso Subproject award from the National Institutes of Health. Project title: “Role of Protein Kinases in Cytomegalovirus Induced Neoplasia.” Project period: June 1, 1991 to May 31, 1995 . Total direct cost for sub project: $348,293.
• Recipient of Minority Scientist Travel Award from the National Institutes of Allergy and Infectious Diseases, NIH to participate in “Workshop on HIV/SIV Pathogenesis and Mucosal Transmission, and Host Factors Responsible for Resistance to HIV Infection and Disease”. Bethesda , MD , March 14-17, 1994 .
• Enhancement of Biology Instruction and Research, LEQSF Support Fund, co-PI, $37,000; 1997-98.
• Project director, NIH-NIEHS Advanced Research Cooperation in Environmental Health Sciences Program pilot project, “The Role of p53 in Mediating Cellular Responses to Combined Butadiene and Cytomegalovirus Exposure,” 8/15/99 to 07/31/05 . $375,000.
• Principal Investigator, NIH-NIEHS Advanced Research Cooperation in Environmental Health Sciences Program Project, “Cellular and Molecular Toxicology of Butadiene.” 8/15/99 to 07/31/05, $5,117,457.

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